Today’s post highlights a research paper out of Italy published this past April. (1) The study compared fasting blood markers for the presence of zonulin, lipopolysaccharides (LPS) and the inflammatory immune protein CD14 between healthy 100-year-olds and two other groups: those under the age of 40 who had the misfortune of having suffered a heart attack Read More →

If I had a cardboard box for a head I’d be sad too.  “Rumination refers to the tendency to repetitively think about the causes, situational factors, and consequences of one’s negative emotional experience. Basically, rumination means that you continuously think about the various aspects of situations that are upsetting. Think about your own tendencies. When Read More →

Abbreviations: BCM7: beta-casomorphin-7 FODMAP: fermentable Oligo-, Di- and Mono-saccharides and Polyols MCP1: monocyte chemotactic protein 1 MPO: myeloperoxidase NCGS: Non-celiac gluten sensitivity SIBO: small intestinal bacterial overgrowth   Today’s post is about an Italian trial confirming that all may not be right with the Western world’s favorite grain. The study is titled Small Amounts of Read More →

Gluten

On February 13th of 2013, I published a post entitled Fibromyalgia, Irritable Bowel Syndrome and Endotoxemia. I made the case that the high prevalence of bowel dysfunction and fibromyalgia was no mere coincidence. In today’s post, I’ll present evidence from a preliminary study out of Spain implicating non-celiac gluten sensitivity (NCGS) as a possible trigger Read More →

  “Professor Colin Pritchard’s latest research published in Public Health journal has found that the sharp rise of dementia and other neurological deaths in people under 74 cannot be put down to the fact that we are living longer – the rise is because a higher proportion of old people are being affected by such Read More →

This a brief post about a recently published paper that found depression, widowhood, living alone and the use of certain anti-depressant drugs were all highly associated with the risk of developing a Clostridium difficile (C. diff.) infection. C. diff. is estimated to cause 7,000 deaths annually in the United States and is prevalent in hospitals Read More →

  Today I want to direct my readers’ attention to a review paper published in 2011, which explores the link between gut flora and both mental and skin health. I’ve already covered some of these mental-health topics here and here. It’s a sad commentary on medicine that the dermatologists who first proposed this connection between Read More →

  Continuing with my coverage of regulatory tight-junction proteins and gut-barrier function, today I want to examine the role of a particular member of our beneficial gut flora community. A 2008 study examined which of the following gut bacteria contributed the most to gut-barrier function (1): Bifidobacterium breve Bifidobacterium infantis Bifidobacterium longum Lactobacillus acidophilus Lactobacillus delbrueckii Read More →

  “Although genetic and biological factors play a major role in the development of obesity, hypertension, insulin resistance, and diabetes, these common disorders that are part of the metabolic syndrome are probably influenced by other factors. Evidence suggests that these disorders are mediated by a complex interplay between genetics, biology, and the environment. Stress, whether Read More →

  Today I want to talk about depression and the evidence implicating increased intestinal permeability and endotoxins in this psychological disorder. Having discussed how endotoxemia impacts your hormonal system, it’s now time to explore what this can mean for your mental state. Wikipedia describes depression as: “…a state of low mood and aversion to activity Read More →

  In the previous two posts I wrote about the different types of gut flora and their physiological functions. In this post, I want to write about what can go terribly wrong when our commensal gut flora are unhappy. Let’s first define the term dysbiosis or disordered flora. I find that this term is thrown around Read More →

  In this post, I want to talk about the various functions beneficial gut flora, and their metabolites play in our health. One thing needs to be mentioned at the start. Many of the following studies were done on rats, mice and other animals. What’s true of animal studies is not always relevant to people Read More →