Ah yes, lactose intolerance…that seminal occurrence of stomach rumbling, gaseous bloat and odoriferous farts strong enough to make a dog vacate the room and that can, with little forewarning, transform into a Rorshach-inspired shart in one’s undergarments or sheets. Magic, pure utter magic! Lactose intolerance is defined by the Mayo Clinic this Read More →

Abbreviations: BCM7: beta-casomorphin-7 FODMAP: fermentable Oligo-, Di- and Mono-saccharides and Polyols MCP1: monocyte chemotactic protein 1 MPO: myeloperoxidase NCGS: Non-celiac gluten sensitivity SIBO: small intestinal bacterial overgrowth   Today’s post is about an Italian trial confirming that all may not be right with the Western world’s favorite grain. The study is titled Small Amounts of Read More →

  Abbreviations: ATIs: amylase and trypsin enzyme inhibitors HFD: high-fat diet HPA axis: hypothalamic-pituitary-adrenal axis IAP: intestinal alkaline phosphatase (aka alkaline phosphatase) IL1-β: interleukin 1 beta LPSs: lipopolysaccharides NF-kB: nuclear factor kappa B PUFAs: polyunsaturated fatty acids TLRs: toll-like receptors TLR4: toll-like receptor 4 TNF-α: tumor necrosis factor alpha WGA: wheat germ agglutinin Today I Read More →

Glass

  Abbreviations: CNS: central nervous system DNA: deoxyribonucleic acid DNMTs: DNA methyltranferases EAAT: excitatory amino acid transporter EAAT3: excitatory amino acid transporter 3 ENS: enteric nervous system FODMAP: Fermentable Oligo-, Di- and Mono-saccharides and Polyols GERD: gastroesophageal reflux disease GSH: glutathione IBS: irritable bowel syndrome LPSs: lipopolysaccharides SAM: S-adenosylmethionine SIFBO: small intestinal fungal and bacterial Read More →

Fresh Apple

  Today’s post will cover a question that repeatedly comes up. It’s a question I’m sure many of you also have: “What diet should I be following when dealing with a gut issue?” Let me first dispense with dietary recommendations that have not been subjected to controlled trials to assess efficacy for controlling annoying or Read More →

Gluten

On February 13th of 2013, I published a post entitled Fibromyalgia, Irritable Bowel Syndrome and Endotoxemia. I made the case that the high prevalence of bowel dysfunction and fibromyalgia was no mere coincidence. In today’s post, I’ll present evidence from a preliminary study out of Spain implicating non-celiac gluten sensitivity (NCGS) as a possible trigger Read More →

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  “Proton-pump inhibitor therapy is now being prescribed for a wide variety of upper gastrointestinal symptoms on the basis that they might be acid induced and therefore may benefit from such treatment. This increasingly liberal usage of these powerful drugs is due to a number of factors, including reduced concerns about potential side effects, reduced Read More →

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  “Ignorance is preferable to error, and he is less remote from the truth who believes nothing than he who believes what is wrong.” Thomas Jefferson     Abbreviations: BCM7: beta-casomorphin-7 C. albicans: Candida albicans FOS: fructooligosaccharide GERD: gastroesophageal reflux disease GI: gastrointestinal H. pylori: Helicobacter pylori, aka Campylobacter pylori IBS: irritable bowel syndrome LES: Read More →

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  “We look for medicine to be an orderly field of knowledge and procedure. But it is not. It is an imperfect science, an enterprise of constantly changing knowledge, uncertain information, fallible individuals, and at the same time lives on the line. There is science in what we do, yes, but also habit, intuition, and Read More →

  The role of stress in negatively impacting the gastrointestinal system has long been recognized. It doesn’t take an Einstein to note a strong correlation between acute psychological stress and the onset of gut feelings that are anything but pleasant. I’ve written about how gut dysbiosis is capable of initiating psychological states like depression and Read More →

  Today’s post will cover some of the research concerning the connection between gut dysbiosis and autism spectrum disorders (ASDs). ASDs are a group of developmental disabilities that cause a whole host of challenges in afflicted children. Among these are difficulties with social interaction, communication, behavior and movement. Males are approximately four times more likely Read More →

  Today I want to continue my discussion of foods, drinks and drugs that tend to aggravate an infected and inflamed gastrointestinal mucosa. Fiber The last post covered gut bacteria’s well-known ability to produce intestinal gas by fermenting fiber. However, dietary fiber, especially insoluble fiber, has other damaging characteristics. As I’ve mentioned before, fiber swells Read More →

  Today I’m going to talk about some dietary changes that may offer some of you symptom relief from your gastrointestinal issues. This is not a cure for small intestinal bacterial overgrowth or inflammatory bowel diseases like Crohn’s disease or ulcerative colitis. These disorders will require reducing gut pathogens and/or overgrowth of fungus like Candida Read More →

  “Although genetic and biological factors play a major role in the development of obesity, hypertension, insulin resistance, and diabetes, these common disorders that are part of the metabolic syndrome are probably influenced by other factors. Evidence suggests that these disorders are mediated by a complex interplay between genetics, biology, and the environment. Stress, whether Read More →

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