Cheshire Cat: Where are you going? Alice: Which way should I go? Cheshire Cat: That depends on where you are going. Alice: I don’t know. Cheshire Cat: Then it doesn’t matter which way you go. ― Lewis Carroll, Alice in Wonderland   Dear Dr. Aaron E. Carroll, You don’t know me from Adam, but I feel Read More →

Glass

  Abbreviations: CNS: central nervous system DNA: deoxyribonucleic acid DNMTs: DNA methyltranferases EAAT: excitatory amino acid transporter EAAT3: excitatory amino acid transporter 3 ENS: enteric nervous system FODMAP: Fermentable Oligo-, Di- and Mono-saccharides and Polyols GERD: gastroesophageal reflux disease GSH: glutathione IBS: irritable bowel syndrome LPSs: lipopolysaccharides SAM: S-adenosylmethionine SIFBO: small intestinal fungal and bacterial Read More →

Gluten

On February 13th of 2013, I published a post entitled Fibromyalgia, Irritable Bowel Syndrome and Endotoxemia. I made the case that the high prevalence of bowel dysfunction and fibromyalgia was no mere coincidence. In today’s post, I’ll present evidence from a preliminary study out of Spain implicating non-celiac gluten sensitivity (NCGS) as a possible trigger Read More →

  Fibromyalgia is a disease characterized by chronic wide-spread pain. These painful areas are spread throughout numerous points on the body. Other symptoms of this disorder are joint stiffness, gastrointestinal upset and mental distress: insomnia, fatigue, depression, anxiety and cognitive dysfunction. Estimates for the prevalence of fibromyalgia range from between 1% to 2% of the Read More →

  In part one of this series, I covered what small intestinal bacterial overgrowth (SIBO) is. This post will concern itself with the diseases it’s associated with. As always, association is not causation so SIBO may be along for the ride and not the initiating cause, or conversely, it might be. It can often be Read More →