Ah yes, lactose intolerance…that seminal occurrence of stomach rumbling, gaseous bloat and odoriferous farts strong enough to make a dog vacate the room and that can, with little forewarning, transform into a Rorshach-inspired shart in one’s undergarments or sheets. Magic, pure utter magic! Lactose intolerance is defined by the Mayo Clinic this Read More →

If I had a cardboard box for a head I’d be sad too.  “Rumination refers to the tendency to repetitively think about the causes, situational factors, and consequences of one’s negative emotional experience. Basically, rumination means that you continuously think about the various aspects of situations that are upsetting. Think about your own tendencies. When Read More →

  Today’s post will cover a ground-breaking study out of Sweden that examined the interactions between gut flora and the blood-brain barrier (BBB). (1) This definition of the blood-brain barrier from Wikipedia sums up its structure and function quite nicely: “The blood–brain barrier (BBB) is a highly selective permeability barrier that separates the circulating blood Read More →

Glass

  Abbreviations: CNS: central nervous system DNA: deoxyribonucleic acid DNMTs: DNA methyltranferases EAAT: excitatory amino acid transporter EAAT3: excitatory amino acid transporter 3 ENS: enteric nervous system FODMAP: Fermentable Oligo-, Di- and Mono-saccharides and Polyols GERD: gastroesophageal reflux disease GSH: glutathione IBS: irritable bowel syndrome LPSs: lipopolysaccharides SAM: S-adenosylmethionine SIFBO: small intestinal fungal and bacterial Read More →

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  Today’s post will cover a question that repeatedly comes up. It’s a question I’m sure many of you also have: “What diet should I be following when dealing with a gut issue?” Let me first dispense with dietary recommendations that have not been subjected to controlled trials to assess efficacy for controlling annoying or Read More →

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  Welcome back from your second and last intermission. I trust the wait wasn’t too long. In today’s post, I’ll be concentrating on how cortisol is regulated by the body, and how these regulatory systems are shaped by immune activation. There is a happy medium where hormone concentrations within a defined lower and upper limit Read More →

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  Over the past year and a half, I’ve spent much my time on this blog detailing the various dietary practices and other conditions that can impair intestinal-barrier function, and for good reason. While our intestines are located within us, as far as the body is concerned, this environment is actually external to it. And Read More →

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  “We look for medicine to be an orderly field of knowledge and procedure. But it is not. It is an imperfect science, an enterprise of constantly changing knowledge, uncertain information, fallible individuals, and at the same time lives on the line. There is science in what we do, yes, but also habit, intuition, and Read More →

  The role of stress in negatively impacting the gastrointestinal system has long been recognized. It doesn’t take an Einstein to note a strong correlation between acute psychological stress and the onset of gut feelings that are anything but pleasant. I’ve written about how gut dysbiosis is capable of initiating psychological states like depression and Read More →

  Today’s post will cover some of the research concerning the connection between gut dysbiosis and autism spectrum disorders (ASDs). ASDs are a group of developmental disabilities that cause a whole host of challenges in afflicted children. Among these are difficulties with social interaction, communication, behavior and movement. Males are approximately four times more likely Read More →

  Today I woke up to a comment from a long-time reader by the name of Sam, and thought my reply would be better served by a short post. Here is Sam’s comment: “Ray, Recently Chris Kresser did a podcast with a question about probiotics. The link is: http://chriskresser.com/solutions-for-snoring-overactive-bladder-and-balancing-goitrogens-in-your-diet Here is an excerpt: ** Most Read More →

  “Professor Colin Pritchard’s latest research published in Public Health journal has found that the sharp rise of dementia and other neurological deaths in people under 74 cannot be put down to the fact that we are living longer – the rise is because a higher proportion of old people are being affected by such Read More →

This a brief post about a recently published paper that found depression, widowhood, living alone and the use of certain anti-depressant drugs were all highly associated with the risk of developing a Clostridium difficile (C. diff.) infection. C. diff. is estimated to cause 7,000 deaths annually in the United States and is prevalent in hospitals Read More →

  What would happen if you fed prebiotics to genetically obese mice or mice fed an obesity-inducing high-fat diet? Would anything change? That’s the subject of today’s post, which covers such an experiment published in 2011. (1) Two different types of mice were used in this study. The ob/ob C57BL/6 mouse and the C57BL/6J mouse. Read More →

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