I haven’t spent much time writing about the oral microbiome on this blog, mainly because most research has until recently focused on the microbial flora of the intestinal tract. It is the colon, after all, where the largest colonies of microbes, both beneficial and pathogenic, reside. But the mouth harbors the second largest quantities Read More →

Coronary

  As long time readers of this blog know, I consider metabolic syndrome (insulin resistance, hypertension, cardiovascular disease, etc.) as fundamentally caused by translocating gut bacteria to the liver and systemic circulation. This explains what initiates what I’ve termed “The Inflammatory-Cortisol Ballet” and the metabolic consequences that flow from that. When it comes to heart Read More →

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  Welcome back from your second and last intermission. I trust the wait wasn’t too long. In today’s post, I’ll be concentrating on how cortisol is regulated by the body, and how these regulatory systems are shaped by immune activation. There is a happy medium where hormone concentrations within a defined lower and upper limit Read More →

  Today I want to continue my discussion of foods, drinks and drugs that tend to aggravate an infected and inflamed gastrointestinal mucosa. Fiber The last post covered gut bacteria’s well-known ability to produce intestinal gas by fermenting fiber. However, dietary fiber, especially insoluble fiber, has other damaging characteristics. As I’ve mentioned before, fiber swells Read More →

This is a very quick post to alert you to a recently published study reported in the journal Gut that found a significant association between strains of the pathogenic oral bacteria Porphyromonas gingivalis and the risk of developing pancreatic cancer. This is highly relevant to my ongoing series on small intestinal bacterial overgrowth as well Read More →