Abbreviations: ASO mice: alpha synuclein over-expressing mice aSyn: alpha-synuclein BBB: Blood Brain Barrier IBD: Inflammatory Bowel Disease IBS: Irritable Bowel Syndrome MSA: multiple system atrophy, Shy–Drager syndrome PD: Parkinson’s Disease SCFAs: Short Chain Fatty Acids SIBO: Small Intestinal Bacterial Overgrowth   According to the Merck Manual, Parkinson’s disease (PD) is defined as: “a slowly progressive, degenerative disorder Read More →

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  “Ignorance is preferable to error, and he is less remote from the truth who believes nothing than he who believes what is wrong.” Thomas Jefferson     Abbreviations: BCM7: beta-casomorphin-7 C. albicans: Candida albicans FOS: fructooligosaccharide GERD: gastroesophageal reflux disease GI: gastrointestinal H. pylori: Helicobacter pylori, aka Campylobacter pylori IBS: irritable bowel syndrome LES: Read More →

  This is part two of my three-part series on insomnia. Today I want to cover how disease and inflammation cause sleep problems. In part one, I discussed some habits that help you get a good night’s sleep. And for a number of you who have occasional sleeplessness, improving your sleep hygiene is all that’s Read More →

  In the previous post, I talked about causes of small intestinal bacterial overgrowth (SIBO) due to compromised gastric barrier function. Today I want to talk about causes due to impaired intestinal movement or motility. But before I do so, I need to mention that being immune compromised predisposes to SIBO. Whether it’s due to Read More →