As long time readers of this blog know, I consider metabolic syndrome (insulin resistance, hypertension, cardiovascular disease, etc.) as fundamentally caused by translocating gut bacteria to the liver and systemic circulation. This explains what initiates what I’ve termed “The Inflammatory-Cortisol Ballet” and the metabolic consequences that flow from that. When it comes to heart Read More →

  In this fifth and final post on gut dysbiosis, endotoxemia and heart disease, I want to explore the role cholesterol plays in all of this. As you know, I consider cholesterol an innocent bystander in this piece, not the villain. So what is cholesterol? Cholesterol is an alcohol but not the same type of Read More →

    In this post, I discussed how unlikely it is that normal digestion of long-chain fatty acids is the source of the pathogens initiating arterial plaque formation. If anything, I showed how protective chylomicrons are in preventing just that. This then leaves us with increased intestinal permeability as the most likely source of translocating Read More →